Norah Jones co-wrote the lyrics for Everybody Needs a Best Friend with Seth MacFarlane, who directed the comedy she also featured in. McFarlane is hosting the Oscars ceremony.
Jones will perform along with other stars, including Adele, who will sing the Skyfall theme -- nominated in the same category -- live for the first time.
Other musical acts include a tribute to Chicago, Dreamgirls and Les Misérables.
Tom Hooper's adaptation of Victor Hugo's work is competing for eight trophies, including Best Original Song with Suddenly.
Listen to the Best Original Song nominees:Before My Time from Chasing IceEverybody Needs a Best Friend from TedPi's Lullaby from Life of PiSkyfall from SkyfallSuddenly from Les Misérables