The statement was in reaction to PM Manmohan Singh's statement in Parliament that Italy would have to face "consequences" for refusing to send back the marines to face trial.
The Italian statement also said Rome had done "everything we could to find an acceptable solution to such case, within the framework of our strong and friendly relations with India, and Italy will continue to do so.
"Italy has conveyed its readiness to start negotiations on such basis. Since there has been no reaction from India in this regard we have come to the conclusion that it is appropriate to solve the legal dispute according to the international law.
"We are a friendly government to Indian government. We want to work it in all possible manners. We've been consistent since day one," Italian ambassador Daniele Mancini said.