Bhupathi has already exited from the mixed doubles with Slovakian partner Daniela Hantuchova.
However, it was a remarkable day for India's Rohan Bopanna as he sealed spot in his first ever Wimbledon semifinals with French partner Edouard Roger-Vasselin.
The 14th seeds knocked out sixth seeded Swede-Canadian combination of Robert Lindstedt and Daniel Nestor with a 7-5 7-6(3) 6-7(4) 6-7(3) 6-2 win in the rain-affected quarter-final, late last night.
Sania Mirza advanced to the pre-quarterfinals of the mixed doubles with Horia Tecau as the second seeded pair downed German team of Martin Emmrich and Julia Goerges 6-3 6-4 in the second round.
Leander Paes had a mixed day as he advanced to the men's doubles semifinals with Czech Radek Stepanek but suffered a tame defeat in the mixed doubles with Chinese partner Saisai Zheng.
Paes and Stepanek, seeded fourth, carved out a 4-6 6-4 6-3 6-4 win over 11th seeded Julien Benneteau of France and Nenad Zimonjic of Serbia.
In the mixed doubles, 15th seventh seeds Paes and Zheng, lost 3-6 3-6 to unseeded American-French combo of Eric Butorac and Alize Cornet.