"So far we can confirm 23 people killed including several Shiite pilgrims and security personal. Seven others are injured," Akbar Durrani, home secretary of Pakistan's southwest Baluchistan province, told AFP.
"Four attackers including two gunmen and two suicide bombers attacked the restaurant in Taftan," he added.
No group has yet come forward to claim the attack. Two devastating bombings in Quetta, the capital of Baluchistan, killed nearly 200 people last year and were claimed by banned Sunni extremist organisation Lashkar-e-Jhangvi (LeJ), which has links to Al-Qaeda.
Nearly 1,000 Shiites have been killed in the past two years in Pakistan, a heavy toll on the community that makes up roughly 20 percent of the country's population of 180 million, which is predominantly Muslim.