"This morning two dead and six injured civilians were brought to our medical facility near Naad Ali and the four most seriously injured were moved to our medical facility at Camp Bastion," Commander Paula Rowe, spokeswoman for the British army in Afghanistan said.
Naad Ali district is in Helmand, the main opium growing region where mostly British forces are engaged in daily gunbattles with Taliban insurgents.
Rowe said an investigation into the Afghan civilian deaths was underway and more information about the circumstances of their deaths would be released later in the day.
"We are always deeply saddened by civilian deaths irrespective of how it is caused," Rowe said.