"I am the happiest director in the world right now," he said in his acceptance speech.
He is only the second French filmmaker honored by his Hollywood peers, following in the footsteps of Franco-Polish director Roman Polanski, who won a best director Oscar in 2003 for The Pianist.
Hazanavicius is married to Berenice Bejo, with whom he has two children, and who starred in The Artist along with Jean Dujardin.