However, the seven-times champion is convinced a combination of his knowledge of the high-speed Spa Francorchamps track and improvements to his car will help him secure a good result next weekend.
"Spa is like my living room; for me, it's clearly the number one race track in the world," said Schumacher, who will become the second driver in history, after Rubens Barrichello, to compete in 300 grands prix.
"It's uncanny how I always seem to have special moments there - my debut, my first win, a world championship victory and many great races.
"The fact that I will also take part in my 300th grand prix at Spa was somehow almost inevitable and we will have to celebrate it in the right way. I'm proud to be just the second driver in the history of the sport to reach this milestone and there's no question that we are looking to have a particularly nice weekend.
"We delivered a good performance in Spa last year; I'll be doing everything possible to drive a strong race."