Mitchell Starc returns after being rested, joining quicks Peter Siddle, Jackson Bird, and MCG man-of-the-match Mitchell Johnson on a green Sydney wicket.
Clarke declared himself fit and will bat at four in place of Shane Watson, ruled out with a calf injury. All-rounder Glenn Maxwell was named 12th man, meaning Usman Khawaja misses out.
Although a dead rubber, Clarke said the game had taken on special significance after veteran middle-order batsman Hussey declared it would be his final Test, with the squad determined to see him off with a flourish.
"When guys retire it's extra special to get a win in that last game for them and I'm certain this Test match will be no different in regards to Michael Hussey," Clarke said.
"I think a lot of guys will be emotional that Mr Cricket's finishing up in Test match cricket after this game... we want to make sure that we send him out on a high," he added.
"Our focus is to win this Test match and to have beaten Sri Lanka 3-0 in this series."
Clarke said his own hunger for success had increased with news of Hussey's retirement and he was confident of a big score after making 106 in Melbourne, adding his hamstring had improved.