Yet Armstrong attorney Tim Herman denied that Armstrong has reached out to USADA chief executive Travis Tygart and David Howman, director general of the World Anti-Doping Agency.
Herman told The Associated Press he had no knowledge of Armstrong considering a confession and said: "When, and if, Lance has something to say, there won't be any secret about it."
Armstrong, who recovered from testicular cancer that had spread to his lungs and brain, won the Tour de France from 1999-2005.
Although he has vehemently denied doping, Armstrong's athletic career crumbled under the weight of a report by USADA detailing allegations of drug use by Armstrong and his teammates on his US Postal Service teams.
The report caused Armstrong to lose most of his personal corporate sponsors and he recently stepped down from the board of Livestrong, the cancer-fighting charity he founded in 1997.
Armstrong is facing other legal hurdles.
The US Department of Justice is considering whether to join a federal whistle-blower lawsuit filed by former Armstrong teammate Floyd Landis. A Dallas-based promotions company has also said it wants to recover several million dollars paid to Armstrong in bonuses for winning the Tour de France. The British newspaper The Sunday Times has sued Armstrong to recover $500,000 paid to him to settle a libel lawsuit.