The show, created by Nicolas Falanci and Cheryl Heuton, used to be aired in the US between January 2003 to March 2010. CBS used to air the show. Zee Cafe has now brought the crime-based drama series to India. The show is about mathematician Charlie Eppes who helpes his brother and FBI special agent Don Eppes (played by Rob Morrow) solve various criminal cases. Rob Marow plays the FBI agent while Charlie's role is donned by David Krumholtz.

Numb3rs also showcases relation between the Eppes brothers and their father Alan Eppes. Encountering mysterious and unsolvable crimes, FBI Special Agent Don Eppes recruits his mathematical genius brother using math to discover the origins of crimes.

The show was received with great fanfare in India as with '#Numb3rsonZCafe' trending on Twitter on Wednesday.