Daren Powell sparked a top-order collapse as West Indies beat England by 93 runs in the third one-day international at Trent Bridge in Nottingham on Saturday to seal a come-from-behind 2-1 series win.
England, set 290 for victory, were bowled out for 196 with more than five overs remaining, fast bowler Powell finishing with four wickets for 40 runs.
Powell took the first three wickets to fall, including dangerman Kevin Pietersen as England slumped to 33 for three inside nine overs and from then on the hosts were always chasing the game.
England had a difficult enough task as it was after West Indies made 289 for five featuring 82 not out from Runako Morton and 82 from captain Chris Gayle, both of whom were dropped early in their innings.
West Indies, as in their 61-run win at Edgbaston on Wednesday which levelled the series at 1-1 after they'd lost Sunday's Lord's opener by 79 runs, scored heavily late on with 116 runs coming off the last 10 overs.
Liam Plunkett (three for 59) and James Anderson (two for 51) shared the wickets between them in an innings where novice seamer Stuart Broad's nine overs cost an expensive 71 runs.
West Indies, beaten 3-0 by England in the preceding Test series, now travel to Dublin for a quadrangular one-day tournament, also featuring Ireland, Scotland and the Netherlands, starting on Tuesday.
England next face India in a three-Test series, starting on July 19 at Lord's. The teams then contest a seven-match one-day series finishing at Lord's on September 8.