At least 10 persons were killed and 35 others injured on Monday night when a tourist bus going to Gujarat fell off a bridge on the Pune-Satara road near the Khambatki Ghat.
Four other vehicles were also damaged on the highway, police said.
The incident occurred at around 10:30pm when the bus heading to Gujarat overturned, apparently while negotiating a sharp gradient.
When other vehicles stopped to rescue the passengers trapped in the bus, a speeding container dashed into four vehicles causing a pile-up.
The rescue operations are over and the injured were rushed to Khandala primary health center and a private hospital in Shirval, said Khandala police inspector Shridhar Jadhav.
(With inputs from agencies)