After days of cramming, two intense earlier debates, and a bitter months-long campaign, Barack Obama and Mitt Romney will come out swinging Monday in their third and final showdown.
With this rematch focusing on foreign policy, the president and his Republican rival will no doubt trade blows over security shortcomings in Libya; how to contain Iran; the roiling crisis in Syria; a rising China; and ending the Afghan war.
It will be Romney's best chance to recover from what are seen as mis-steps in criticizing Obama's handling of the September 11 attack on the US consulate in Benghazi, Libya that left four Americans dead.
Romney will be aiming to use the head-to-head clash to press his broader point that the Libya attack and other anti-American violence in the Middle East are signs that Obama's foreign policy is "unraveling before our very eyes."
Romney is a former businessman who appears more comfortable addressing economic problems. He has stumbled at times on international issues, and his foreign tour last summer was widely panned.
But Obama too has issues; a Pew Research Center poll shows his advantage on foreign policy shrinking to just four points over Romney, after being up 15 points in September .
Obama's mission: remind Americans of his successes as commander-in-chief, such as ending the Iraq war and neutralizing Osama bin Laden, while convincing them that his rival is a throwback to the George W. Bush era who doesn't have the experience or resolve to steer the nation through a crisis.
Critical toss-up state Florida is the fitting battleground for the main event, which comes just 15 days before the election and promises to be among the most watched 90 minutes of the entire 2012 campaign.
With Romney dominating the first face-to-face encounter in Colorado, and Obama widely seen as bouncing back to take the second outside New York city, the stakes for Round 3 are monumental.
Heightening the drama, a new major NBC/Wall Street Journal poll conducted after the second debate shows the rivals dead even, at 47% apiece among likely voters.
Even with the zeroing in on international affairs, both camps admitted Sunday that their candidates will seek to draw discussion back to the issue most pressing for voters: the US economy.
"I think the most important thing we can do as a country on our foreign policy is strengthen our economy here at home," Chicago Mayor Rahm Emanuel, Obama's former chief of staff, said on Sunday.
Romney has spoken repeatedly about how a strong domestic economy projects US strength and leadership abroad.
He and Obama will will face questions about crises like Libya, which has remained a front-burner issue some six weeks after the September 11 attack.
Many analysts said Obama bested Romney on the Libya issue in their testy second debate, when Romney accused the president of delaying a full two weeks before describing the Benghazi attack as terrorism.
Obama shot back that he called it an act of terror on the day after the attack, challenging Romney to "check the transcript" and berating him for trying to make political gains after the attack.
Romney will seek to put pressure on Obama over Iran and its nuclear program, arguing that presidential weakness has emboldened Tehran, and that if elected he would work to prevent the Islamic republic from acquiring a nuclear weapons "capability," a lower threshold than advocated by the White House.
Complicating the scenario, just 48 hours before the debate, The New York Times reported that US officials said Iran was ready to hold one-on-one talks with Washington.
The White House shot down the story, but Republican surrogates used it to warn Obama about potentially isolating allies who have worked for years on getting Iran to halt its nuclear program.
"The other thing that gets interesting about the story, if it's accurate, it sounds like the US is taking a position that we're likely to jettison our allies," Senator Rob Portman told NBC's "Meet the Press" on Sunday.
"The last thing we would want to do is abandon our allies on this and make it a one-on-one negotiation."