An Australian study, led by an Indian-origin scientist, has found that six-year-olds who spent the most time watching television, using a computer or playing video games had narrower arteries in the back of their eyes — a marker of future cardiovascular risk.
The first-of-its-kind study showed that more sedentary behavior such as "screen time" was associated with an average narrowing of 2.3 microns in the retinal arteriolar caliber. A micron is one thousandth of a millimeter or one-25th of a thousandth of an inch.
In the study, six- to seven-year-olds who regularly participated in outdoor physical activity had 2.2 microns wider average retinal arteriolar compared to those children with the lowest level of activity.
The magnitude of the narrowing associated with each hour of television/computer viewing was similar to that associated with 10 millimeters of mercury (mm HG) increase in systolic blood pressure in children, researchers said.
"We found that children with a high level of physical activity had a more beneficial microvascular profile compared to those with the lowest levels of physical activity," said Bamini Gopinath, lead author and senior research fellow at the Center for Vision Research at the University of Sydney.
"This suggests that unhealthy lifestyle factors may influence microcirculation early in life and increase the risk of cardiovascular disease and hypertension later in life,” she said.
The study included 1,492 children in 34 primary schools in Sydney, Australia. Parents answered a 193-item questionnaire, providing the number of hours spent each week in indoor and outdoor physical activity and sedentary activity such as watching television, videogames, computer time and reading.
On average, the children spent 1.9 hours per day in screen time and 36 minutes a day in total physical activity. Children in the highest levels of physical activity at just over an hour or more had significantly wider average retinal arteriolar caliber than those spending just under half an hour or less per day.
Increased screen time was associated with narrower average retinal arteriolar diameter after adjusting for age, sex, ethnicity, iris color, length of the eyeball, BMI, birth weight and blood pressure. Each hour per day of TV viewing time was associated on average with 1.53 microns narrower retinal arteriolar caliber.
"Excessive screen time leads to less physical activity, unhealthy dietary habits and weight gain," she said.
"Replacing one hour a day of screen time with physical activity could be effective in buffering the effects of sedentariness on the retinal microvasculature in children. Free play should be promoted and schools should have a mandatory two hours a week in physical activity for children,” she added.
The study has been published in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.