DR SUNIL Pradhan, professor of neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), gives yet another ‘clinical sign’ to the medical science. The sign has ‘appeared’ in the world’s topmost neurology journal — The Archives of Neurology, on Monday. Dr Pradhan is already a world-renowned neurologist.
The clinical sign diagnoses just by physical examination if a person has Miyoshi Myopachy (a kind of muscular dystrophy). The disease currently has no cure.
There are about 30 different kinds of muscular dystrophy. But only a few have clinical signs by which they can be diagnosed. And Dr Pradhan has discovery of as many as three signs to his credit that can help diagnose three different kinds of dystrophy.
Before this Dr Pradhan had discovered the ‘Polyhill Sign’ and the ‘Valley Sign’.
The Valley Sign is now know as ‘Pradhan Sign’ in medical science. Polyhill Sign diagnoses the ‘Facioscapulohumeral Dystrophy’ while the Pradhan Sign diagnoses ‘Duchenne Muscular Dystrophy’.
A clinical sign is a sign through which a doctor, just by a physical examination of a person, can diagnose a disease.
Dr Pradhan has named the new discovery as ‘Calf-head Sign’ and he worked for about six years on it. “If a doctor asks a person to be in a certain kind of posture then a trophy kind of sign appears on his back. This trophy has two heads which look like head of baby calf. If this sign appears on a person’s back in that particular posture then the person is a patient of Miyoshi Myopachy — a kind of wasting of muscles.
“Miyoshi Myopachy is a kind of dystrophy discovered by a Japanese scientist Dr Miyoshi about two decades ago. The disease is a genetic one. Till now, to diagnose it surgical extraction of muscle was required and then this extract is put through tests,” he said.
In Miyoshi Myopachy, generally a person starts wasting his muscles from the age 10 to 20 and then continues wasting muscles. Calf-head sign makes it very easy and totally without any expenditure. It currently has no cure. Scientists are working to find a cure through gene-therapy or stem cell transplant.
Dr Pradhan already is a Dr Shanti Swarup Bhatnagar Award recipient. He also has two awards from ICMR.