TRS chief K Chandrasekhar Rao, CPI Deputy General Secretary S Sudhakar Reddy, Union Ministers Jaipal Reddy and Renuka Chaudhary are among the prominent Lok Sabha candidates whose fate will be decided in the first phase of elections in Andhra Pradesh on April 16.
The TRS president, who won from Karimnagar Lok Sabha seat in 2004 general elections and thrust bypolls on the constituency twice in 2006 and 2008, is now contesting from Mahabubnagar seat.
According to his critics, Rao has shifted to Mahabubnagar as he no longer considered Karimnagar to be a safe bet for him, where is being challenged by sitting Congress MP D Vithal Rao and BJPs K Yadagiri Reddy.
Mahabubnagar is one the most backward districts in the country, with as many as three lakh people having migrated from here in 2005 for work.
The soft-spoken CPI deputy general secretary is seeking re-election from his traditional Nalgonda constituency. The Congress nominee in the constituency is G Sukhender Reddy, a senior TDP leader who switched sides after being denied ticket to contest the Lok Sabha seat.
Union Urban Development Minister S Jaipal Reddy, who represented Miryalguda in the outgoing Lok Sabha, is seeking election from the newly-created Chevella seat, as his constituency had been scrapped in the delimitation excercise.
Even before he could launch his campaign in Chevella, Reddy had to deal with the stiff opposition from a section of his partymen who alleged that he is an "outsider".
Reddy's main rivals are A P Jitendra Reddy of TDP and BJP's Baddam Bal Reddy, who is putting up a strong fight as he enjoys a good support in some of the assembly segments under Chevella.
The high-profile Union Women and Child Development Minister Renuka Chaudhury too is seeking re-election from her Khammam parliamentary seat.
She will be locking horns with TDPs Nama Nageswara Rao, who will be making a determined bid to foil the minister's attempt to score a hat-trick.
Meanwhile, the Medak Lok Sabha, which was once represented by late Indira Gandhi, is witnessing a keen contest between actress-turned-politician Vijaya Santhi of TRS and C Ravindranath of Congress, who is a political novice.
Vijaya Santhi, who shifted her base from Chennai to Hyderabad and took up the separate Telangana cause, has now merged her Talli Telangana Party with the TRS.
Other leaders, whose fate will be sealed during the first phase of Lok Sabha polls include-- TDP leader K Yerran Naidu, who is keen on retaining his Srikakulam seat in north coastal Andhra and V Kalyani of the newly formed Praja Rajyam Party (PRP).
Naidu will be facing a tough challenge from K Krupa Rani of Congress in this coastal seat bordering Orissa.
Another Union Minister and late N T Rama Rao's daughter D Purandeswari, is contesting from Visakhapatnam Lok Sabha seat.
Purandeswari, who represented Bapatla in the outgoing Lok Sabha, had to shift to Visakhapatnam as the seat was reserved for Schedule Caste's post-delimitation.
Taking on the articulate Purandeswari is TDP candidate M V V S Murthy, who had won from the constituency earlier. The BJP nominee for the seat D V Subba Rao, who enjoys a enviable reputation in the city, will give her a tough challenge.
Rao, a veteran lawyer, served as the president of the Bar Council of India and also as a manager of the Indian cricket team.
Another prominent personality in the fray is state BJP president Bandaru Dattatreya who is trying his luck from Secunderabad Lok Sabha seat.
Dattatreya, a former Union Minister, lost the 2004 elections from Secunderabad to his Congress rival M Anjan Kumar Yadav.
The two are pitted against each other and Dattatreya appears to have an edge as he has a reputation of being an accessible and down to earth mass leader.