Dunst's performances in Universal's comedy Bring it On, which opened number- one at the box office, and the critically acclaimed Virgin Suicides with James Woods and Kathleen Turner, made critics and fans alike stand up and take notice of her blossoming talent. In 2001, she won rave reviews for her role as a troubled girl in Disney's Crazy/Beautiful.

Dunst was nominated for a Golden Globe for her performance in Interview with the Vampire, for which she also received the Blockbuster Video Award for Best Supporting Newcomer, an MTV award for Best Breakthrough Artist and the Saturn Award for Best Young Actress. Dunst recently received an MTV award for Best Actress for her role in Spider-Man, and shared an additional Best Kiss MTV honor with Tobey Maguire, for their memorable lip lock in the film. Earlier in her career, Dunst was named by The Hollywood Reporter as Best Young Star for her portrayal of a teenage prostitute in NBC's hit series, ER.

ALFRED MOLINA (Dr Octavius) is an accomplished and versatile actor with over fifty film, television and theatre productions to his credit.

Molina recently starred as Diego Rivera in Frida, opposite Salma Hayek, Edward Norton, Geoffrey Rush and Ashley Judd. His performance earned him Best Supporting Actor nominations from BAFTA, the Screen Actors Guild, the Chicago Film Critics Association and the Broadcast Critics Association. Molina also appeared in the recent Columbia Pictures thriller Identity, opposite John Cusack, Ray Liotta and Amanda Peet; and in Plots With A View, with Brenda Blethyn, Naomi Watts and Christopher Walken. He appeared opposite Juliet Binoche and Johnny Depp in director Lasse Hallstrom's critically acclaimed Chocolat.

JAMES FRANCO (Harry Osborn) received a Golden Globe Award for his critically acclaimed performance in the title role of the TNT film James Dean, directed by Mark Rydell. His portrayal of Dean also earned him an Emmy nomination as well as a Screen Actors Guild Award nomination. With Spider-Man 2, Franco reprises his role as Harry Osborn, having portrayed the character in Spider-Man.

Franco will next be seen in Robert Altman's The Company.