Indian challenge ended at the ATP Indian Wells Masters with the shock first round defeats of Mahesh Bhupathi and Sania Mirza in their respective events, in Indian Wells.
The third seeded pair of Bhupathi and Canadian Daniel Nestor bowed out of the men's doubles with a 4-6 6-7 (4) defeat against Spaniard Feliciano Lopez and Milos Raonic of Canada.
Rohan Bopanna had also made a first round exit in the same event with American partner Rajeev Ram.
In the women's doubles, eighth seeded team of Sania and America's Bethanie Mattek-Sands went down fighting 7-6 (8) 3-6 6-10 against American Lisa Raymond and Samantha Stosur of Australia in their opening round clash.
Somdev Devvarman had failed to enter for the main draw of the men's singles with the first-round defeat in the qualifiers.
Federer and Nadal win, Ferrer goes out
While Roger Federer and Rafa Nadal won their opening matches in straight sets on Saturday, world No 4 David Ferrer became the first top seed to make an early exit. Spaniard Ferrer, a winner of two ATP titles this year who is known for his speed across the court, was ousted 3-6 6-4 6-3 by big-serving South African Kevin Anderson in the second round at the Indian Wells Tennis Garden.
Four-times champion Federer, however, wasted little time in pounding Uzbekistan's Denis Istomin 6-2. 6-3 with a ruthless display of seemingly effortless movement and razor sharp shot-making.
In a heavily anticipated evening encounter, Spaniard Nadal overcame early resistance from American Ryan Harrison to win 7-6 6-2 in his first match on a hardcourt surface in 346 days, following a left knee injury.
Nadal, a twice former champion at Indian Wells, did not appear to be in any discomfort after being sidelined for seven months last year and he dominated the second set before wrapping up victory in just over an hour and a half. "I am satisfied to be in the next round," said the Spaniard who has enjoyed a successful tournament run on clay in recent weeks, winning two ATP titles after reaching three finals.