The Indian challenge ended at the ATP Legg Mason Classic after the opening round defeat of Rohan Bopanna and his Pakistani partner Aisam ul haq Qureshi in the doubles event in Washington.
The fourth seeded Indo-Pak pair fell 6-7(1) 7-6(6) 3-10 to the unseeded Mark Knowles of Bahamas and Xavier Malisse of Belgium after putting up a gallant fight for one hour and 47 minutes.
Somdev has already exited from the singles event following a second round defeat to Marcos Baghdatis of Cyprus.
Knowles and Malisse came into the tournament with a title win at Farmer's Classic last week. They had beaten the pair of Somdev and Treat Conrad Huey of Philippines.