Top seed Nikolay Davydenko dispatched American Robert Kendrick 7-6 6-3 on Tuesday to advance to the third round of the New Haven Open.
The Russian world number eight Davydenko outlasted big-serving Kendrick in the first set, and cruised through the second to continue his tune-up for the US Open, where he has twice reached the semi-finals.
Eighth seed Mardy Fish was knocked out by fellow American Rajeev Ram 6-3 6-3, after squandering five break points.
Second seed Fernando Verdasco of Spain advanced with a straight-set victory and joins Jose Acasuso of Argentina and French veteran Fabrice Santoro in the third round.
In the women's draw, former world number one Amelie Mauresmo breezed into the third round with a 6-1 6-1 demolition of Ukraine's Alona Bondarenko, while France's Marion Bartoli, and Samantha Stosur of Australia advanced to the second round.