After snatching the initiative at the top of Group G with yet another away victory, England will look to rectify its poor recent home record to move a step closer to next year's European Championship finals.
England maintained its 100% away run in qualifying by brushing aside Bulgaria 3-0 on Friday, leaving the team three points clear after closest rival Montenegro's surprise 2-1 loss at Wales.
With Montenegro not on action on Tuesday, Fabio Capello's men will move into a six-point lead by beating Wales, but that would require them ending a four-match winless streak at Wembley.
England winger Theo Walcott said, "We need to take our away form to Wembley. It will come."
Switzerland hosts fellow also-ran Bulgaria in the group's other match.