Top seed and defending champion Roger Federer showed no mercy for best friend Stanislas Wawrinka on Sunday when he handed his Olympic gold medal-winning teammate a 6-3, 7-6 (7/5), 6-2 French Open thumping.
World number one Federer nows faces Robin Soderling, the Swedish fifth seed who he defeated in the final last year.
Soderling sent four-time champion Rafael Nadal crashing to a shock defeat last year on his way to a first Grand Slam final, but Federer will be buoyed by his perfect record of 12 wins in 12 matches against the big-hitting Swede.
Soderling reached the quarterfinals with a brutal 6-4, 6-4, 6-2 demolition of Croatian 10th seed Marin Cilic.
French hopes of a first men's champion since Yannick Noah in 1983 fizzled out when eighth-seeded Jo-Wilfried Tsonga was forced to retire from his last 16 clash with Russian 11th seed Mikhail Youzhny with a groin injury.
Henin shows Sharapova the door
Four-time champion Justine Henin displayed all her trademark grit to see off Maria Sharapova 6-2, 3-6, 6-3 and reach the French Open fourth round here on Sunday.
The Belgian 22nd seed hit back from 0-2 and 0-40 down in the last set against her fellow former world number one to claim victory and set up a last-eight meeting with Australian seventh seed Samantha Stosur. The match resumed on Sunday after play was suspended at one set all amid fading light on Saturday evening.
Paes-Dlouhy move on, Bopanna-Qureshi out
Defending champions Leander Paes and Lucas Dlouhy stormed into the quarterfinals of the doubles event after a 6-3, 6-4 victory over Santiago Gonzalez and Travis RettenMayer.
Rohan Bopanna and Aisam-ul-Haq Qureshi's doubles campaign was cut short in the second round with a straight-set defeat against local pair of Julien Benneteau and Michael Llodra. The unseeded Indo-Pak pair lost the men's doubles clash 5-7, 3-6 to the 15th seed.