Levante stunned 10-man Real Madrid 1-0 on Sunday, with Arouna Kone's second-half goal giving the Spanish powerhouse its first loss of the league season.
While Barcelona routed Osasuna 8-0 for its biggest home win under coach Pep Guardiola on Saturday, a lackluster Madrid was held scoreless for the third consecutive visit to Ciutat de Valencia stadium.
Madrid played a man down from the 40th after Sami Khedira received his second yellow card.
Cristiano Ronaldo came off the bench at halftime to try and spark Madrid, but Kone converted Levante's numerical advantage into the 68th-minute winner.
The loss left Madrid one point behind Barcelona and two points behind league leader Valencia.