Manchester United will attempt to put their Champions League frustrations behind them on the domestic front with the chance to revive their Premier League hopes against Newcastle.
A 2-2 midweek draw at home to Benfica meant United must now avoid defeat in their final group match at FC Basel next month to be sure of qualifying for the knockout rounds of Europe's leading club competition. On the domestic front, United trail Premier League leaders Manchester City, who travel to Liverpool on Sunday, by five points going into the weekend.
Newcastle lost their first Premier League match of the season with a 3-1 defeat at Manchester City last weekend, while United's 6-1 hammering by Roberto Mancini's side is their only loss of the campaign.
United know that another stumble at Old Trafford will give City the chance to extend their advantage at the top of the table to eight points.
Villas-Boas in search of Wolves respite
LONDON: Chelsea manager Andre Villas-Boas will have had better weeks as he prepares to arrest his side's slump in form at home.
But the arrival of Wolverhampton on Saturday will give him solace, as they have failed to win on their travels since the opening day of the Premier League season.
Villas-Boas is under pressure just three months into his first season at Chelsea, after losing back-to-back home matches against Liverpool and Arsenal.
Atletico aim to end 12 years of hurt
MADRID: Real Madrid and Barcelona resume their own private battle at the top of La Liga on Saturday, Real entertaining city rivals Atletico Madrid, while Barcelona visit the outskirts of the capital city to take on struggling Getafe. Madrid will look to defend their three-point lead over Barcelona by stretching their current run of 12 consecutive wins against their long-suffering neighbour.