Striker Miroslav Klose and midfielder Marco Reus have pulled out of Germany's friendly against Ukraine.
Klose has an inflamed tendon on his left knee while Reus is down with a stomach flu.
The German Football Federation says Klose will return for next week's friendly against the Netherlands. Reus' return will depend on his condition.
It is the fifth time will be Reus is forced to sit out Germany matches because of health problems.