Fifth seeds Leander Paes and Radek Stepanek were eliminated from the ATP Cincinnati Masters following their defeat against Vasek Pospisil and Jack Sock in men's doubles in Cincinnati on Wednesday.
Paes and Stepanek lost 1-6 6-4 8-10 in the second round of the USD 4,017,355 hard court event in the run up to the US Open, the last Grand Slam tournament of the season.
The Canadian-American combo had also ousted the Indo-Pak pair of Rohan Bopanna and Aisam-ul-haq Qureshi earlier in the tournament.
India's challenge is still alive in the women's tournament as Sania Mirza and Cara Black have got a bye in the first round.
The fourth seeded Indo-Zimbabwean pair faces Spain's Anabel Medina Garrigues and Kazakhstan's Yaroslava Shvedova in the USD 2,567,000 Western and Southern Open.