Sania Mirza once again fell at the second round stage when she lost in straight sets to Meng Yuan at the $600,000 East West Bank Classic tournament.
The 16th seed Indian lost to her unseeded Chinese opponent 4-6 3-6 in one and a half hour contest to crash out of the hard court WTA event.
Sania borke Yuan once and dropped her own serve twice to go down in the first set.
Then in the second, Sania could convert just three out of six breakpoints while the Chinese cashed in on all the five breakpoints to snatch the match away from the Indian.
The defeat came as a big jolt to Indian fans, who have pinned hopes on India's numero uno woman player to win a medal at Beijing Olympics.
Sania had also lost her second round matches at WTA events in Birmingham, s'Hertogenbosch and at Wimbledon singles last month.
Last week she had lost to a British qualifier in the first round of the Stanford WTA tournament.