People wait in line to buy Apple Inc's iPhone 5 as an Apple fan shows his iPad outside Apple Store in Tokyo's Ginza district. Reuters/Yuriko Nakao
The early total for the iPhone 5 topped sales of the iPhone 4S, which sold more than 4 million units in its first weekend after Apple introduced it in October 2011.
Expectations for new Apple products are so high that Wall Street appeared not to be wowed by the latest numbers. Investors sent shares of the stock down 1.4% at $690.14 in mid-morning trade.
"It appears investors were disappointed with the slowdown in growth in the first weekend," said BTIG analyst Walter Piecyk.
Apple said while the majority of iPhone 5 pre-orders have been shipped to customers, many were scheduled to go out in October.
The world's most valuable technology company is being closely watched for any supplier problems that may slow down the smartphone production.
"We believe that sales could have potentially been much higher if not for supply constraints," William Power, an analyst with Baird Equity Research, wrote in a note.
He forecast Apple selling 8 million to 10 million units in the fiscal fourth quarter ending in September.
One of Apple's key suppliers for screens, Sharp Corp , is struggling with high costs and scrambling to raise funds to pay debt.
Taiwan's Foxconn Technology Group, which assembles iPhones, closed a plant in China on Monday after about 2,000 workers were involved in a brawl in a company dormitory. It was not clear how long the shutdown would last.
Additionally, Apple is facing stiff competition from smartphones that run on Google Inc's Android software, which has become the most-used mobile operating system in the world. Apple's key supplier as well as rival, Samsung Electronics Co Ltd, has taken the lead in smartphone sales.
The iPhone 5 has been one of Apple's most aggressive international rollouts to date. The phone will be available 31 countries on Sept. 28 and in more than 100 countries by the end of the year.
"Expectations for Apple are always white hot," said Colin Gillis, a research analyst with BGC. "It's not just enough for them to break records but to smash them."
Apple signaled last week that pre-orders outstripped initial supply and that many phones would not be available until October.
The iPhone is Apple's highest-margin product and accounts for half of its annual revenues.
On Friday, fans lined up at stores in cities around the world to get their hands on the new phone, which is thinner and lighter and has a bigger screen.