Over 10 protesters were killed in clashes with police near the Egyptian Interior Ministry building in Cairo in the early hours of Sunday, RIA Novosti said quoting Al Jazeera.
The protestors' crowd was trying to storm the building, located in the centre of the Egyptian capital,
forcing police to open fire, the TV channel Al Jazeera stated.
In the Faiyum Governorate, an administrative division, located about 81 miles (130 km) to the southwest of Cairo, unknown gunmen shot dead the chief of a local prison, freeing several hundred prisoners, the report stated Sunday.
Anti-government protests continued for the fifth day Saturday in Egypt with tens of thousands demanding President Hosni Mubarak step down after three decades in power.
Earlier, Al Jazeera said about 100 people had been killed in clashes with police in Cairo and other Egyptian cities.
On Saturday, Mubarak dismissed the country's government and appointed a former civil aviation minister, Ahmed Shafiq, as the new prime minister, ordering him to form a new cabinet.