ratified the earlier decision to expel a former railway minister, Liu Zhijun.
More than 2270 delegates from across the country will attend the main meeting, beginning on Thursday.
According to state-run Xinhua, investigations had found that Bo seriously violated CPC disciplines while managing Dalian City, Liaoning Province, and the ministry of commerce, as well as serving the Political Bureau member and the Chongqing Party chief.
Investigations showed Bo had abused his power, made severe mistakes and borne major responsibility in an incident concerning former Chongqing vice mayor Wang Lijun's entering, without permission, the US Consulate General in Chengdu, and an intentional homicide case involving Bogu Kailai, Bo's wife.
Liu has been under investigation since February 2011, when he was removed from his government post on suspicion of "serious disciplinary violations."
"Liu's removal is also believed to be linked to the high-speed train collision last July that killed 40 passengers and injured 172 others, the tragedy having been blamed on improper management," Xinhua reported.
He was found to have used his position to seek huge illegal profits for private businessmen, which caused great economic losses and negative social influence and had “taken massive bribes and bore the major responsibility for severe corruption in the railways system.”
A document released after the meeting said it must be fully understood that anti-corruption was a "long-term, complicated and tough battle," given the changing situation as well as complicated and critical challenges faced by the Party.
It added that the whole Party was confronted with growing danger of "lacking in drive, incompetence, divorce from the people, and corruption."
It said the CPC will stick to the guideline of curbing graft by both penalty and preventive measures while focusing more on prevention, according to the document.
"Fighting corruption and promoting cleanness and honesty in a resolute manner is a consistent political stand held by the CPC and also a key political issue that is of major concern to the people," said the communique.