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HindustanTimes Sat,26 May 2012
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Now, a jab 'that can halt diabetes in just six days'
PTI
London, May 11, 2010
First Published: 16:51 IST(11/5/2010)
Last Updated: 16:54 IST(11/5/2010)
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In what could be called a major breakthrough, scientists have developed a new drug which they claim could halt diabetes in its tracks in just six days. The drug, called Otelixizumab, which appears to halt the rapid decline in the body's production of insulin, works by switching off the
immune system's self-destruct mechanism that causes Type 1 diabetes, say the scientists.

This halts damage to the pancreas, allowing it to carry on producing its own insulin, the Daily Mail reported.

Currently undergoing clinical trials, the drug seems to work best when given as soon as possible after someone has been diagnosed with Type 1 diabetes. It is given as a daily jab for six days in a row.

Type 1 diabetes, which tends to affect young people, occurs when the immune system starts to attack healthy tissues such as the insulin-producing cells in the pancreas.

In fact, the new drug works by altering the balance between certain types of cell in the immune system. It contains a very specific antibody - a protein that is designed to home in on certain cells in the body.

In this case, the antibody targets a marker found only on the T effector cells. Once the drug locks onto the cells, it stops them destroying insulin-producing cells in pancreas.

The findings, published in the 'Diabetologia' journal, show that otelixizumab can either halt or dramatically reduce need for insulin injections among newly diagnosed diabetics.


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