Spain's Interior Minister Alfredo Perez Rubalcaba has said that the two men suspected of involvement in the 2006 Madrid airport bombing have been arrested by the police.
Rubalcaba on Saturday confirmed that the Spanish and French police have arrested three suspected members of the Basque separatist group ETA Friday in southern France, two of who are suspects of the Madrid bombing.
The deadly bombing December 30, 2006, at the Madrid airport destroyed a multi-storey parking garage and killed two people.
Peace talks between the Spanish government and ETA halted following the bombing, and the group called off its 15-month ceasefire in June 2007.
In early January, Spanish police arrested two other ETA members suspected of involvement in the attack.
Rubalcaba said the Spanish police would enhance cooperation with French in the fight against ETA, which has already proved fruitful.
ETA, which is classified as a terrorist group by the US and the European Union, has waged a four-decade campaign of violence to seek independence for a Basque state, killing hundreds of people.