Golden age of GM crops
Golden rice, a new strain that boosts vitamin A levels and reduces blindness, is about to be sown in the Philippines.world Updated: Feb 12, 2013 01:16 IST
Scientists say they have seen the future of genetically modified foods and have concluded that it is orange or, more precisely, golden. In a few months, golden rice - normal rice that has been genetically modified to provide vitamin A to counter blindness and other diseases in children in the developing world - will be given to farmers in the Philippines for planting in paddy fields.
Thirty years after scientists first revealed they had created the world's first GM crop, hopes that their potential to ease global malnutrition problems may be realised at last. Bangladesh and Indonesia have indicated they are ready to accept golden rice in the wake of the Philippines' decision, and other nations, including India, have also said that they are considering planting it.
"Vitamin A deficiency is deadly," said Adrian Dubock, a member of the Golden Rice project. "It affects children's immune systems and kills around two million every year in developing countries. It is also a major cause of blindness in the third world. Boosting levels of vitamin A in rice provides a simple, straightforward way to put that right."
Recent tests have revealed that a substantial amount of vitamin A can be obtained by eating only 60g of cooked golden rice. "This has enormous potential," said Dubock.
But scientists' satisfaction over the Golden Rice project has been tempered by the fact that it has taken an extraordinarily long time for the GM crop to be approved. Golden rice was first developed in 1999, but its development and cultivation has been opposed vehemently by campaigners who have flatly refused to accept that it could deliver enough vitamin A, and who have also argued the crop's introduction in the developing world would make farmers increasingly dependent on western industry. The crop has become the cause of the anti-GM movement, which sees golden rice as a tool of global capitalism.
This view is rejected by the scientists involved. "We have developed this in conjunction with organisations such as the Bill and Melinda Gates Foundation as a way of alleviating a real health problem in the developing world," says Dubock. "No one is going to make money out of it. The companies involved in developing some of the technologies have waived their licences just to get this off the ground."
This view is shared by Mark Lynas, an environmental campaigner and one of the founders of the anti-GM crop movement. He has publicly apologised for opposing the planting of GM crops in Britain. "The first generation of GM crops were suspect, I believed then, but the case for continued opposition to new generations - which provide life-saving vitamins for starving people - is no longer justifiable. You cannot call yourself a humanitarian and be opposed to GM crops today."
"All the time, opponents to golden rice insisted, year after year, that it would not be able to produce vitamin A in those who ate it," said Peter Beyer, golden rice's co-creator. "For example, it was alleged by Greenpeace that people would have to eat several kilograms of the stuff to get any benefit."
Two studies, both published in the American Journal of Clinical Nutrition, demolished this claim. The first, in 2009, was based on a group of healthy adult volunteers in the US and showed that golden rice's beta-carotene was easily taken up into the bloodstream.
The second trial was carried out by American and Chinese researchers and published last year. It was carried out on Chinese children, aged between six and eight, and showed that a bowl of cooked golden rice, between 100g and 150g, could provide 60% of the recommended intake of vitamin A for young people.
The fate of golden rice is therefore important, as professor Jonathan Jones of the John Innes Centre points out. "When I started making GM plants 30 years ago, I did wonder if there might be unknown unknowns. But the evidence now is clear. GM food and crops are as safe as non-GM food and crops."
The Golden Rice project has had one beneficial knock-on effect, however. It has triggered a series of similar crop modification programmes that aim to tackle vitamin A deficiency through use of other GM foodstuffs. One example is provided by the golden banana, which has been created by scientists led by professor James Dale of Queensland University in Australia.
"In Uganda, where the banana is a key source of nutrition, there is considerable vitamin A deficiency and also iron deficiency in diets," he said. "The former not only causes blindness but leaves children less able to fight disease which, in Africa, is particularly serious. The latter, iron deficiency, causes blood disorders."
To put this right, Dale and his team have found ways to boost beta-carotene levels in bananas. Now they are working on boosting iron levels as well. The team expects to have developed a golden banana, that will raise both iron and vitamin A levels, by the end of the decade.
The result of the team's work will be similar to golden rice: peeled, the pale fruit will be carrot-coloured. And if that sounds strange, it is worth noting that carrots were not originally orange. In the 17th century they were mostly yellow or purple, but were bred to be orange by Dutch farmers in tribute to the ruling House of Orange.