A bomb exploded in Dera Ghazi Khan, a town on the border of Punjab and Frontier province in Pakistan, killing 27, including two women and two children, and injuring at least 60.
The blast occurred at a taxi stand near the residence of a provincial minister.
The lawmaker whose home was hit, Zulfiqar Khosa, is a senior member of the Pakistan Muslim League-N party, which is in charge of the Punjab government but is in the opposition in the federal government.
The blast in Dera Ghazi Khan is the latest in a series of suicide and other explosions that have killed more than 500 people in Pakistan since October.
The bloodshed has been blamed on the Tehreek Taliban Pakistan which is retaliating for an army offensive in the Waziristan area. The bomb left a massive crater and was heard from a half-a-mile away.