The US coalition troops killed 35 militants and wounded another 13 during a clash in southern Afghanistan, the US military said in a statement.
A joint Afghan-coalition patrol was ambushed on Thursday in Zabul province's Day Chopan district, before returning fire and calling in airstrikes on the militants, the statement said.
Following the clash, troops assisted the wounded militants before they were taken into Afghan custody. There were no injuries among Afghan or coalition troops.
The clash follows another battle in the eastern Paktika province early on Thursday, where 34 militants, including Arab and Pakistanis, were killed.
The violence is escalating in Afghanistan, as additional US troops move into the country and try to reverse the Taliban gains of the last three years.