US envoy Richard Holbrooke was due to meet President Hamid Karzai on Saturday on the second full day of a visit to Afghanistan to assess US led efforts to tackle a Taliban led insurgency.
The meeting, due in the evening, comes as Afghanistan marks 20 years since the withdrawal of Soviet forces after a 10 year resistance that the Taliban claims has parallels with its own battle against US and other troops.
Karzai's office would not comment on the agenda, but the president is likely to reiterate demands for an end to civilian casualties in US led military operations and more focus on militant bases in neighbouring Pakistan.
Afghanistan has been heartened by recent strikes on extremist sanctuaries in the Pakistani tribal belt, which it says give vital support to the insurgency.
A new suspected US missile attack on Saturday killed at least 20 militants in a Pakistani tribal district near the Afghan border, a senior security official told AFP.
Holbrooke, President Barack Obama's regional troubleshooter, arrived in Afghanistan late on Thursday from Pakistan where military commanders say they urgently need equipment to tackle the Taliban threat.
He has already met Afghan authorities and politicians including from the opposition, military commanders and international ambassadors as part of wide-ranging discussions that will inform a new US policy here.
The envoy, who has a reputation as a hard nosed diplomat, has insisted a new approach is required to turn the strife torn country around that involves all of Afghanistan's neighbours and in particular Pakistan.
"It is going to be a long, difficult struggle," he said at an international conference in Germany last week, adding he believed it was going to be "much tougher than Iraq."
Holbrooke's appointment underscores Obama's commitment to refocus on Afghanistan, which in 2008 suffered its deadliest year in the insurgency led by the Taliban who were removed from government in a US led invasion in late 2001.
Obama is expected to decide soon whether to send more US troops to Afghanistan with the US commander here, General David McKiernan, requesting up to 30,000 additional troops.
If they are approved for deployment, it would nearly double the size of the US force, which currently numbers around 37,000.
The expected deployment is seen as one reason behind a delay in presidential elections to August with fears that the weakening security could jeopardise the poll.
Karzai is standing for re-election at the ballot the second ever presidential vote in war battered Afghanistan amid doubts over his relations with the new US administration after firm support from the previous government.
He admitted last week that there was some "light wrestling" with his US allies, mainly over civilian casualties which have caused deep anger and resentment among Afghans and risk public support for his government.
The Taliban try to use such casualties to fuel suspicion of the troops, whom they call "infidels" and "invaders" like the Soviets who entered Afghanistan in December 1979.
The arrival of the Red Army led to a resistance by mujahideen (holy fighters) that drew in Pakistan and the United States and resulted in a Soviet withdrawal on February 15, 1989, being marked with a public holiday in Afghanistan on Saturday.
The Taliban claims it too is involved in a jihad and regularly warns of a similar "cruel defeat" for the thousands of US and NATO-led troops who are in Afghanistan at the request of the government.