Exposure to benzene in pregnancy linked to greater incidence of birth defects
High exposure to benzene during pregnancy is associated with low birth weight, an increased risk of childhood leukemia and a greater incidence of birth defects such as spina bifid, found a study.Updated: Nov 13, 2017 19:00 IST
In a bid to study the health impacts related to living near fracking sites where contaminants, including volatile organic compounds, are released, researchers at the Universite de Montreal Public Health Research Institute studied a group of pregnant women who live in the area.
The findings suggest exposure to chemicals associated with fracking have been linked to impaired brain function in infants, children, and young adults.
Fracking is the process of drilling down into the earth before a high-pressure water mixture is directed at the rock to release the gas inside.
High concentrations of muconic acid - a degradation product of benzene (a volatile, toxic and carcinogenic compound) - were detected in the urine of 29 pregnant women who participated in the pilot study.
Their median concentration of muconic acid was approximately 3.5 times higher in these women than in the general Canadian population.
In five of the 29 participants, the concentration of muconic acid surpassed the biological exposure index (BEI), a measure developed by the American Conference of Governmental Industrial Hygienists (ACGIH) to protect the health of people in the workplace. Caron-Beraudoin informed the five women of the results and communicated with their attending physicians. Guidelines of acceptable amounts of muconic acid in urine exist only for the workplace; there are none for the general population.
Not beyond a reasonable doubt
“Although the levels of muconic acid found in the participants’ urine cannot prove beyond a reasonable doubt that they were exposed to high levels of benzene, these results do clearly demonstrate the importance of exploring human exposure to environmental contaminants in natural-gas (fracking) regions,” said Marc-Andre Verner, the lead researcher on the study.
“Muconic acid is also a degradation product of sorbic acid, which is often used as a preservative in the food industry,” said Caron-Beaudoin. “However, we believe that diet alone is unlikely to explain the concentrations we found in our participants. A more extensive study needs to be conducted with additional measures - to test the air and drinking water, for example - to confirm or refute the results of our pilot study.”
Health hazards of benzene include birth defects
The health impacts of benzene are well-documented. “High exposure to benzene during pregnancy is associated with low birth weight, an increased risk of childhood leukemia and a greater incidence of birth defects such as spina bifida,” said Caron-Beaudoin.
“We were therefore very concerned when we discovered high levels of muconic acid in the urine of pregnant women.”
It should be noted that there are multiple routes of exposure to benzene, including inhaling cigarette smoke, filling your car’s gas tank, driving, and drinking benzene-contaminated water.
The findings have been published in Environment International.
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First Published: Nov 13, 2017 18:11 IST