Here's how signals from muscle protect from dementia | Health - Hindustan Times
close_game
close_game

Here's how signals from muscle protect from dementia

ANI | , Washington Dc
Mar 27, 2021 07:17 PM IST

Scientists at St. Jude Children's Research Hospital study how do different parts of the body communicate and how signals sent from skeletal muscle affect the brain.

Scientists at St. Jude Children's Research Hospital study how do different parts of the body communicate and how signals sent from skeletal muscle affect the brain. The team studied fruit flies and cutting-edge brain cell models called organoids. They focused on the signals muscles send when stressed. The researchers found that stress signals rely on an enzyme called Amyrel amylase and its product, the disaccharide maltose.

Representational image(Unsplash)
Representational image(Unsplash)

The scientists showed that mimicking the stress signals can protect the brain and retina from ageing. The signals work by preventing the buildup of misfolded protein aggregates. Findings suggested that tailoring this signalling may potentially help combat neurodegenerative conditions like age-related dementia and Alzheimer's disease.

Hindustan Times - your fastest source for breaking news! Read now.

"We found that a stress response induced in muscle could impact not only the muscle but also promote protein quality control in distant tissues like the brain and retina," said Fabio Demontis, PhD, of St. Jude Developmental Neurobiology. "This stress response was actually protecting those tissues during ageing."

Catch your daily dose of Fashion, Health, Festivals, Travel, Relationship, Recipe and all the other Latest Lifestyle News on Hindustan Times Website and APPs
This story has been published from a wire agency feed without modifications to the text. Only the headline has been changed.
SHARE THIS ARTICLE ON
Share this article
SHARE
Story Saved
Live Score
OPEN APP
Saved Articles
Following
My Reads
Sign out
New Delhi 0C
Monday, March 04, 2024
Start 14 Days Free Trial Subscribe Now
Follow Us On