Wonder pill? Aspirin cuts bile duct cancer risk, claims study | health and fitness | Hindustan Times
Today in New Delhi, India
Aug 17, 2017-Thursday
-°C
New Delhi
  • Humidity
    -
  • Wind
    -

Wonder pill? Aspirin cuts bile duct cancer risk, claims study

A new research claims that long-term use of aspirin — a common painkiller that treats fever and inflammation — can cut the risk of bile duct cancer.

health and fitness Updated: Apr 22, 2016 07:40 IST
Regular, long-term use of aspirin is associated with a decreased risk of a number of different cancer types, particularly gastrointestinal cancers, say researchers.
Regular, long-term use of aspirin is associated with a decreased risk of a number of different cancer types, particularly gastrointestinal cancers, say researchers.(Shutterstock)

A new research claims that long-term use of aspirin — a common painkiller that treats fever and inflammation — can cut the risk of bile duct cancer.

Bile duct cancer — also called cholangiocarcinoma — is an aggressive type of cancer that forms in the slender tubes (bile ducts) carrying digestive fluids through the liver.

Read: Matters of the heart: Pop an aspirin daily and stay healthy in your 50s

“Regular, long-term use of aspirin is associated with a decreased risk of a number of different cancer types, particularly gastrointestinal cancers,” said one of the researchers, Lewis Roberts, gastroenterologist and hepatologist at Mayo Clinic in the US.

The findings showed that individuals who took aspirin had a more than a two-and-half to three-and-half times lesser chance of developing bile duct cancer, compared to individuals who did not take aspirin.

The researchers found that aspirin, with it’s anti-inflammatory properties, can decrease the risk of bile duct cancer by lessening inflammation through slowing down an enzyme called cyclo-oxygenase (COX), which is known to promote inflammation.

Aspirin, with it’s anti-inflammatory properties, can decrease the risk of bile duct cancer by lessening inflammation. (Shutterstock)

“We know that continuous unremitting inflammation is one of the main factors promoting bile duct cancer,” Roberts added in the paper published in the journal Hepatology.

In addition to the COX enzyme pathway, according to previous studies, aspirin also blocks additional cell-signaling cascades that promote cancer development.

Read: Doctors are misdiagnosing heart diseases as aspirin allergy

However, it is not yet certain that aspirin is safe to use for cancer prevention.

The team said additional confirmatory studies are needed before aspirin can be recommended for use in preventing bile duct cancer.

Bile duct cancer occurs mostly in people over 50 and can cause symptoms, such as yellowing of the skin and eyes, intense itchiness of the skin, and white stools. It progresses quickly and is difficult to treat.

Follow @htlifeandstyle for more.