Eight coaches of the Jagdalpur-Bhubaneswar Hirakhand express train derailed near Kuneru station, about 30 kms from Rayagada in Odisha, late on Saturday night.
There were no immediate reports of casualties though the railway ministry said rescue and relief operations had been immediately initiated.
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The ministry said railway minister Suresh Prabhu was monitoring the situation, and had directed officials to ensure that prompt medical relief.
About four medical vans have been sent to the location while helplines have been set up in Visakhapatnam, Vizianagaram and Rayagada.
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