A health worker holds up a vial of Covishield at PSRI Hospital in New Delhi.(HT Photo)
A health worker holds up a vial of Covishield at PSRI Hospital in New Delhi.(HT Photo)

Health ministry releases list of blood clot symptoms to watch out for after taking Covishield

India has reported clotting and bleeding events in just 0.61 for every million doses of the Covishield vaccine administered to people, the health ministry said.
By hindustantimes.com | Edited by Amit Chaturvedi, Hindustan Times, New Delhi
PUBLISHED ON MAY 18, 2021 08:23 AM IST

The Union health ministry said on Monday that the number of blood clot cases in people who received AstraZeneca's Covid-19 vaccine (called Covishield) in India was "minuscule". Covishield - one of three shots granted emergency approval in India - is the most widely used in the country and is manufactured by Pune-based Serum Institute (SII).

Watch: NITI Aayog explains Covishield dose gap increase to 10-12 week


"AEFI (Adverse Event Following Immunisation) data in India showed that there is a very miniscule but definitive risk of thromboembolic events," the health ministry said in a statement, citing a report by the National AEFI Committee.

Also Read: Details of thromboembolic events after Covid-19 vaccination

Thromboembolic events refer to the formation of a clot in a blood vessel that might also break loose and be carried by the bloodstream to plug another vessel.

The ministry separately released advisories to healthcare workers and vaccine beneficiaries to encourage people to be aware of suspected thromboembolic symptoms. These symptoms, the ministry said, occur within 20 days of taking a shot (particularly Covishield) and asked the beneficiaries to report to the health facility where vaccine was administered.

The list of symptoms mentioned in the ministry's advisory are:

  • breathlessness;
  • pain in chest;
  • pain in limbs/pain on pressing limbs or swelling in limbs (arm or calf);
  • multiple, pinhead size red spots or bruising of skin in an area beyond the injection site;
  • persistent abdominal pain with or without vomiting;
  • seizures in the absence of previous history of seizures with or without vomiting;
  • severe and persistent headache with or without vomiting (in the absence of previous history of migraine or chronic headache);
  • weakness/paralysis of limbs or any particular side or part of the body (including face);
  • persistent vomiting without any obvious reason;
  • blurred vision or pain in eyes or having double vision;
  • change in mental status or having confusion or depressed level of consciousness
  • Any other symptom or health condition which is of concern to the recipient or the family

According to the AEFI Committee, it has completed an in-depth case review of 498 serious and severe events, of which 26 cases have been reported to be potential thromboembolic (formation of a clot in a blood vessel that might also break loose and carried by the bloodstream to plug another vessel) events - following the administration of Covishield vaccine - with a reporting rate of 0.61 cases per million doses.

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