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Cardiologist warns most heart attacks don’t come from big blockages; explains what really causes them

Published on: Dec 6, 2025, 12:00:17 IST
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Heart attacks are often caused by hidden plaque, not just blockages, experts warn. (Freepik)
Heart attacks are often caused by hidden plaque, not just blockages, experts warn. (Freepik)

Think heart attacks come from major blockages? A cardiologist says the real danger lies in tiny, unstable plaques that stay silent until they suddenly rupture.

We tend to think heart attacks strike only when an artery is severely clogged, but that’s an oversimplified picture. Heart disease is far more complicated and, in many cases, dangerously quiet. Dr Dmitry Yaranov, a Tennessee-based cardiologist who specialises in heart transplants, explains this in his November 29 Instagram post, where he breaks down why the biggest threats often come from hidden plaque, not the large, obvious blockages most people worry about. (Also read: AIIMS neurologist warns 'stop scrolling your phone first thing in morning’; shares how it can affect your mental health )

Where do most heart attacks actually come from

According to Dr Yaranov, a stress test only tells doctors how the heart performs under physical pressure. It measures blood flow when the heart is pushed to work harder. But what it doesn’t show is what’s happening inside the artery walls, the place where most heart attacks actually begin. “A stress test looks at traffic flow. A CT coronary angiogram looks at the road itself, the cracks, potholes, and weak spots,” he said.

While many assume heart attacks occur because of large or obvious blockages, Dr Yaranov clarified that most cardiac events are caused by small, soft, inflamed plaques. These plaques don’t obstruct blood flow enough to show up on a stress test, yet they can rupture suddenly, leading to a heart attack without warning.

This is why, he explained, cardiology is shifting its focus from asking whether there is a blockage to understanding whether there is any underlying coronary artery disease.“You can ace a stress test and still carry silent, unstable plaque,” Dr Yaranov noted.

Which test actually reveals hidden heart disease

For individuals with symptoms, a family history of heart issues, diabetes, or high-risk profiles, Dr Yaranov recommends a CT Coronary Angiogram (CCTA) as a more accurate diagnostic tool. Unlike a stress test, which shows how well blood is flowing, a CCTA visualises the artery walls in detail, revealing plaque buildup, weak spots, and early signs of disease.

“CCTA is the tool that actually sees the disease, not the shadow, not the guess, the disease itself,” he added. As heart disease continues to rise, experts stress the importance of early detection and more precise screening tools. A normal stress test is reassuring, but it’s no guarantee your arteries are healthy.

Note to readers: This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

This article is for informational purposes only and not a substitute for professional medical advice.

  • Akanksha Agnihotri
    ABOUT THE AUTHOR
    Akanksha Agnihotri

    Akanksha Agnihotri is a lifestyle journalist with over 3 years of experience. She is a psychology graduate and holds a postgraduate diploma in Radio and Television Journalism from the Indian Institute of Mass Communication, Delhi, where she graduated as a gold medalist. Originally from Bhopal, the beautiful capital of Madhya Pradesh, she draws inspiration from the city’s rich cultural heritage and layered storytelling traditions that subtly shape her narrative voice. She writes extensively about fashion, beauty, health, relationships, culture, and food, exploring everything from trending styles and runway moments to wellness routines and mindful living. Passionate about meaningful and candid conversations, she enjoys interviewing celebrities, doctors, designers, and film personalities, diving into discussions on fitness, beauty, mental health, and everything fun in between. With a keen eye for trends and a thoughtful understanding of human behaviour, she brings depth, sensitivity, and authenticity to her stories, ensuring they resonate with a wide and diverse audience. When she’s not working, you’ll usually find her lost in a book, planning her next mountain trek, or mapping out spontaneous travel escapes. She loves discovering new authors, revisiting old favourites, and spending quiet afternoons in museums soaking in art, history, and culture. An avid bird-watching enthusiast, she finds joy in early morning walks, spotting rare birds, and reconnecting with nature. Whether sipping coffee while journaling her thoughts or exploring hidden corners of a new city, she constantly seeks inspiration in everyday moments that often turn into compelling story ideas.Read More

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