‘We want to see our medicines succeed’: Manas AI's Siddhartha Mukherjee on human bias | HTLS 2026

Manas AI CEO Siddhartha Mukherjee has warned that bias in artificial intelligence could pose a major challenge for the medical sector, describing it as “bias in, bias out” or “Bibo”. Speaking at the Hindustan Times Leadership Summit 2026 in New Delhi, Mukherjee said human beings are deeply biased and explained how medicine developed randomised, blinded clinical trials to reduce the influence of human bias on research outcomes. He said AI could potentially help accelerate clinical trials through synthetic controls, using historical or simulated data as a comparison for patients receiving treatment. However, he cautioned that biased input data could produce biased AI outputs, making the problem particularly significant in medicine. Mukherjee also questioned whether the growing computing power behind AI should necessarily be changed, even if radical alternatives are possible.