The BSE benchmark Sensex on Friday fell by over 75 points in opening trade due to profit-booking at higher levels amid a weakening trend on other Asian bourses.
The 30-share index, which had gained 48.61 points on Thursday, fell by 75.07 points, or 0.40%, to 18,683.56, with stocks of oil and gas, IT and banking sectors succumbing to profit-booking.
Similarly, the wide-based National Stock Exchange Nifty Index moved down by 23.20 points, or 0.40%, to 5,682.10.
Brokers said apart from profit-booking by investors after on Thursday's gains, a weak trend in the Asian region ahead of US economic growth figures to be released later in the day, mainly led to a fall in stock prices.
Meanwhile in the Asian region, Japan's Nikkei was down by 0.89%, while Hong Kong's Hang Seng index shed 0.79%.
The US Dow Jones Industrial Average ended 0.20% higher in on Thursday's trade.