Delhi health minister Satyendar Jain.(PTI)
Delhi health minister Satyendar Jain.(PTI)

Delhi health minister Satyendar Jain bats for plasma therapy

ICMR had conducted a pan-India study to determine the role of plasma therapy, and the Union health ministry had added it as one of the investigational therapies in the national protocol for treating Covid-19 patients.
By Anonna Dutt | Hindustan Times, New Delhi
UPDATED ON OCT 22, 2020 06:41 AM IST

New Delhi: Delhi health minister Satyendar Jain on Wednesday said that over 2,000 people have benefitted from plasma therapy in Delhi, a day after reports that Centre was considering to remove it from clinical management protocol for the coronavirus disease (Covid-19),

“A study done by ICMR and AIIMS did not see any breakthrough maybe. But our trial is underway and it is of course being done with the permission of ICMR. We have seen benefits of the therapy, with over 2,000 people having received convalescent plasma from our bank at ILBS. I have myself benefited from the therapy,” said Jain in an interaction with media.

ICMR had conducted a pan-India study to determine the role of plasma therapy, and the Union health ministry had added it as one of the investigational therapies in the national protocol for treating Covid-19 patients.

However, Dr Balram Bhargava, director general, India Council of Medical Research (ICMR) had said on Tuesday, “We have had discussions at the National Task Force (NTF) and we are discussing further with the Joint Monitoring Committee. This (plasma therapy) may be deleted from the national guidelines.”

 

The trial conducted by the Indian Council of Medical Research across 39 sites for the effectiveness of the therapy in Covid-19 patients, showed that there were no difference in the proportion of patients who progressed to severe disease and those who died between the group that received convalescent plasma and the other who received standard care without plasma.

Convalescent plasma therapy is a well-established method used to treat infections and autoimmune diseases. For Covid-19, a blood component called plasma that is rich in virus-fighting antibodies is taken from patients who have recovered and given to those still fighting the infection.

AAP national spokesperson Raghav Chadha said the removal of the therapy from the protocol would be a “perfunctory act”. “To remove Convalescent Plasma Therapy from Clinical Management Protocol based on a single study (i.e. ICMR Trial) in which even antibody titers of the plasma were not taken into account is a perfunctory act — in a situation where no definitive therapy exists till date,” Chadha tweeted.

Click here for full Covid-19 coverage

“The world’s largest observational study on Convalescent Plasma Therapy conducted on 35,322 Covid patients by Mayo Clinic reported favorable outcomes with lower mortality in patients who received the therapy early in the course of disease with higher levels of antibodies,” he tweeted.

The study by Mayo clinic shows that the seven-day mortality rate reduced in patients transfused within three days of diagnosis as compared to those who were given the therapy later, especially if the donor had high levels of antibodies.

Reviewing the effectiveness of the therapy, Dr Manish Soneja, additional professor in the department of medicine at AIIMS, said, “The PLACID trial from India shows that the results were pretty similar in the group that received plasma therapy and the group that was given standard care. There were some limitations of the study such as many of the patients who were given the therapy already had high levels of neutralising antibody (that prevents the spread of a particular virus, Sars-CoV-2 in this case) at admission. However, this replicates the real-life situation with the facility for testing for neutralising antibodies not available in most places.”

“As for globally, a Chocrane (a library of collated medical evidence) that has looked at 19 studies shows that the therapy is not effective in reducing the all cause mortality. Improvement in clinical symptoms wasn’t really there,” he said.

However, after ICMR had released the data from its trial Dr SK Sarin, director of Institute of Liver and Biliary Sciences (ILBS) which is coordinating Delhi’s plasma trial said, “The ICMR study actually reconfirms the findings of our small study – it shows that the oxygen requirement went down in the patients who received plasma therapy, the duration for which they remained breathless reduced, and the group that received plasma tested negative for the virus quicker than the control group. What needs to be factored in is that the therapy was administered late, after two days of symptoms in most trial participant; it works best when given early. Also, many of the donors in the study did not have a high titre (concentration) of the neutralising antibodies,” Dr Sarin had said.

“For the study, the all-cause mortality at 28-days has been considered, I think a shorter duration has to be chosen because mortality could be because of other complications as well,” he said.

A large-scale study of 400 participants is currently underway at Lok Nayak hospital and Rajiv Gandhi Super Speciality hospital in collaboration with ILBS.

SHARE THIS ARTICLE ON
Close
Delhi recorded 239 new Covid-19 cases on Monday, lower than the infections reported over the weekend, the health bulletin released by the government showed. (ANI )
Delhi recorded 239 new Covid-19 cases on Monday, lower than the infections reported over the weekend, the health bulletin released by the government showed. (ANI )

Free Covid-19 vaccine for all in govt facilities: Sisodia in Delhi Budget 2021

By hindustantimes.com | Written by Meenakshi Ray, New Delhi
PUBLISHED ON MAR 09, 2021 12:32 PM IST
As Manish Sisodia presented a 69,000 crore budget for Delhi, he allocated 9934 crore or 14% of the total budget to health.
Close
Deputy chief minister Manish Sisodia oversees Delhi's budget for 2021-22 on a tablet device, on Monday. He presented the national capital's first paperless budget today.(PTI Photo)
Deputy chief minister Manish Sisodia oversees Delhi's budget for 2021-22 on a tablet device, on Monday. He presented the national capital's first paperless budget today.(PTI Photo)

Deshbhakti curriculum, Sainik school: Sisodia's budget proposals for education

By hindustantimes.com | Edited by Amit Chaturvedi
UPDATED ON MAR 09, 2021 12:32 PM IST
Manish Sisodia further said that the apart from these, the AAP government will also take three major steps in the field of education: new syllabus from nursery to Class 8, setting up of Delhi's own school education board and starting 100 schools of excellence in the national capital.
Close
Representational image.
Representational image.

Delhi HC asks Centre to help fund treatment of minor suffering from rare disease

By Richa Banka
PUBLISHED ON MAR 09, 2021 11:41 AM IST
Justice Najmi Waziri, on March 4, took note of the submission by the child’s mother who had contended that there is some hope for treatment of her child in the US, where ameliorative treatment has been administered to some patients similarly afflicted
Close
The government aims to increase Delhi's per capita income and make it equivalent to that of Singapore by 2047, Sisodia said.
The government aims to increase Delhi's per capita income and make it equivalent to that of Singapore by 2047, Sisodia said.

Delhi Budget: Sisodia proposes outlay of 69,000 crore, focuses on patriotism

By hindustantimes.com | Written by Meenakshi Ray
PUBLISHED ON MAR 09, 2021 11:41 AM IST
Manish Sisodia said the government will allocate funds for a series of events to be held across the city over 75 weeks from starting March 12 to celebrate 75 years of Independence in India.
Close
Delhi deputy chief minister Manish Sisodia oversees the state budget 2021-22 on a tablet device, ahead of its announcement in the Delhi assembly, in New Delhi on March 8. (PTI)
Delhi deputy chief minister Manish Sisodia oversees the state budget 2021-22 on a tablet device, ahead of its announcement in the Delhi assembly, in New Delhi on March 8. (PTI)

Delhi’s per capita income dropped in 2020-21: What the economic survey says

By HT Correspondent | Edited by Sameer
PUBLISHED ON MAR 09, 2021 10:17 AM IST
The state gross domestic product shrunk by around 5.68%, according to the economic survey tabled by the Delhi government in the assembly on Monday, which cited impact from the Covid-19 outbreak
Close
Women join the protesting farmers at Tikri border in New Delhi on March 8. (AFP)
Women join the protesting farmers at Tikri border in New Delhi on March 8. (AFP)

Farmers’ protest: Curbs in place, traffic continues to be hit

By HT Correspondent | Edited by Smriti Sinha
PUBLISHED ON MAR 09, 2021 08:36 AM IST
For motorists coming to Delhi from UP, the Ghazipur border remains closed. Traffic police have advised commuters to take routes passing through Anand Vihar, DND, Loni DND and Apsara borders
Close
Representational image. (Arvind Yadav/HT PHOTO)
Representational image. (Arvind Yadav/HT PHOTO)

Delhi’s air quality deteriorates, may improve later today

By HT Correspondent | Edited by Zara Khan
PUBLISHED ON MAR 09, 2021 08:19 AM IST
IMD scientists said that there is a forecast of strong, cool winds to blow from the eastern side of Delhi on Tuesday, which will help improve the air quality of the city and help bring down the rising mercury levels
Close
The government data also showed that the average levels of major pollutants, including that of PM10, PM2.5, and nitrogen dioxide, have been decreasing steadily over the years. (ANI Photo)
The government data also showed that the average levels of major pollutants, including that of PM10, PM2.5, and nitrogen dioxide, have been decreasing steadily over the years. (ANI Photo)

Lockdown improved city’s air, experts say time to think local

By HT Correspondent, New Delhi
PUBLISHED ON MAR 09, 2021 04:21 AM IST
  • Experts, however, attributed the reduction to the “unprecedented conditions” brought about by the Covid-19 lockdown and called for reforms to curb pollution by local and regional factors.
Close
“All economies have been dented by Covid-19 and so has the economy of Delhi." said Delhi Lieutenant Governor Anil Baijal during the Budget Session (PTI Photo/ Arun Sharma)(PTI)
“All economies have been dented by Covid-19 and so has the economy of Delhi." said Delhi Lieutenant Governor Anil Baijal during the Budget Session (PTI Photo/ Arun Sharma)(PTI)

L-G outlines govt plans, opens Budget session

By HT Correspondent, New Delhi
PUBLISHED ON MAR 09, 2021 04:07 AM IST
  • The L-G also noted that the economy of the Capital shrunk by 5.6% due to the pandemic.
Close
Metro services in Delhi were suspended from March 22, 2020, to September 6, due to the nationwide lockdown.(Sanchit Khanna/HT PHOTO)
Metro services in Delhi were suspended from March 22, 2020, to September 6, due to the nationwide lockdown.(Sanchit Khanna/HT PHOTO)

Covid-19 hits Metro ridership, total vehicles in city at 11.8mn

By HT Correspondent, New Delhi
PUBLISHED ON MAR 09, 2021 04:01 AM IST
  • Transport experts say the Metro ridership may have also suffered on account of the free bus rides for women scheme
Close
Education has remained the focus of the AAP ever since they were elected to power in Delhi.(Sanchit Khanna / HT Photo)
Education has remained the focus of the AAP ever since they were elected to power in Delhi.(Sanchit Khanna / HT Photo)

Govt stays invested in students, on track to achieving targets

By Fareeha Iftikhar, New Delhi
PUBLISHED ON MAR 09, 2021 03:56 AM IST
  • According to the outcome budget, education was among the sectors where the government was able to achieve maximum targets.
Close
L-G Anil Baijal and chief minister Arvind Kejriwal arrive for the Budget session at the Delhi assembly on Monday. Raj K Raj/HT PHOTO
L-G Anil Baijal and chief minister Arvind Kejriwal arrive for the Budget session at the Delhi assembly on Monday. Raj K Raj/HT PHOTO

Ashram underpass gets revised June deadline

By HT Correspondent, New Delhi
UPDATED ON MAR 09, 2021 03:51 AM IST
  • In the outcome budget, which was also presented on Monday, the government said that 40% of the work on the underpass was completed until December last year.
Close
36% of 87.8 lakh Covid-19 tests were done using the more accurate RT-PCR method.( Photo by Raj K Raj/ Hindustan Times)
36% of 87.8 lakh Covid-19 tests were done using the more accurate RT-PCR method.( Photo by Raj K Raj/ Hindustan Times)

Delhi among states that tested the most for Covid

By Anonna Dutt, New Delhi
PUBLISHED ON MAR 09, 2021 03:39 AM IST
  • There were 87.8 lakh Covid-19 tests conducted in the city till December 31, 2020.
Close
Delhi police commissioner SN Shrivastava said the force wants to mark the day in two ways – one, by letting the women force take command roles and manage priority policing and, two, by felicitating women police officers who have done exceptional work in their fields. (ANI Photo)
Delhi police commissioner SN Shrivastava said the force wants to mark the day in two ways – one, by letting the women force take command roles and manage priority policing and, two, by felicitating women police officers who have done exceptional work in their fields. (ANI Photo)

In Delhi, Women personnel take over

By HT Correspondent, New Delhi
PUBLISHED ON MAR 09, 2021 03:10 AM IST
  • On the occasion, the Delhi Police also honoured 22 women personnel for their remarkable efforts beyond the call of duty during the Covid-19 pandemic period
Close
According to the DCP, a call was received at 1.40pm on Monday at the Parliament Street police station regarding the body of a child found that had been discovered behind the National Media Centre. (PTI Photo/Arun Sharma) (PTI)
According to the DCP, a call was received at 1.40pm on Monday at the Parliament Street police station regarding the body of a child found that had been discovered behind the National Media Centre. (PTI Photo/Arun Sharma) (PTI)

Body of newborn found buried in sand at Raisina Road, probe launched

By HT Correspondent, New Delhi
PUBLISHED ON MAR 09, 2021 03:01 AM IST
  • A police team immediately rushed to the spot and found that the body had been buried in a mound of sand that had been unloaded there for construction work at the media centre.
Close
SHARE
Story Saved
OPEN APP