FIFA World Cup 2018: Cristiano Ronaldo, Lionel Messi’s exit sends Twitter into overdrive

The first round of FIFA World Cup 2018 knockout matches saw both Cristiano Ronaldo and Lionel Messi eliminated from the tournament, reviving arguments, jokes and debates on social media.

The knockout round of the FIFA World Cup has only just begun but the tournament has already lost it’s biggest stars as both Lionel Messi’s Argentina and Cristiano Ronaldo’s Portugal were eliminated from the tournament on Saturday. (FULL FIFA WORLD CUP 2018 COVERAGE)

This combo photo shows Argentina's Lionel Messi (R) and Portugal's Cristiano Ronaldo reacting during their round of 16 matches against France and Uruguay, respectively, at the 2018 FIFA World Cup at the Kazan Arena and at the Fisht Stadium in Sochi, Russia, on June 30, 2018. (AP)

Argentina suffered a 4-3 loss at the hands of France in the first round of 16 game of the tournament while Portugal were dealt the knockout blow by Uruguay. (FRA v ARG report) (URU v POR report)

The defeats also saw Ronaldo and Messi - widely considered among the greatest to have ever played the game - continued their embarrassing run of never having scored in the knockout stages of the World Cup.

Check out some of the best reactions below.

Uruguay will next take on France in the quarter-finals of the tournament on July 6, 2018.