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Can vaccine composition be changed according to Delta, Delta Plus? Here's what ICMR chief says

Changing the composition of the vaccine according to variants of interest and variants of concern is the way forward, if there is a need, ICMR chief Dr Balram Bhargava has said.

Published on: Jun 27, 2021, 21:43:23 IST
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The Indian Council of Medical Research is studying the effect of vaccines against various variants of the SARS-CoV-2 virus as at a later stage a change in vaccine composition can be suggested according to the circulating variants of concern and variants of interest, ICMR chief Dr Balram Bhargava has recently said. Vaccine composition is easily modifiable, especially that of the mRNA vaccines, but whole virus inactivated vaccines can also be modified. But this is only a need-based solution that the ICMR has thought of as a way forward, Dr Bhargava said.

Changing the composition on mRNA vaccines is easy, Dr Balram Bhargava said, (REUTERS)
Changing the composition on mRNA vaccines is easy, Dr Balram Bhargava said, (REUTERS)

As the Covid-19 virus is replicating, its variants have become a reason for concern as every variant appear to be stronger than the previous one. For example, the Alpha variant which was first reported in the United Kingdom has now got overpowered by the Delta variant, first reported in India. Now, the Delta variant is responsible for 90 per cent of Covid-19 cases in the United Kingdom. Several other countries have now reported this variant.

A slide from ICMR chief's recent presentation where he talked about need-based change in vaccine composition.

It is crucial to study whether the existing vaccines are equally effective against these emerging variants, whether there is any change in the severity in the cases, or in the requirement of hospitalisation. A comparative study of vaccines' performance against Alpha, Beta, Gamma and Delta is available, according to which Covishield and Covaxin are effective against all these variants.

 
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