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Pollutants suppress male characters

Some pesticides like DDT, dioxins and chemicals cause the suppression.

Updated on: Jan 05, 2005 01:41 PM IST
PTI | By , Ahmedabad
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Pollutants such as DDT and dioxins are feared to have caused sex ratio alterations in Italy and Russia through suppression of male characteristics, a US scientist said.

HT Image
HT Image

Some pesticides like DDT, dioxins and chemicals used in refrigerator compressors have "antoandrogenic effect", leading to suppression of expression of male characteristics, Prof Debdas Mukherjee, senior scientist at US Environmental Protection Agency, Cincinnati, told the 92nd Session of Indian Science Congress.

Seveso in Italy and two places in Russia experienced the phenomenon wherein more female births were reported, skewing the birth ratio, he said, adding it might be due to presence of these pollutants in the atmosphere.

Mukherjee said he studied two female cases at the MD Anderson Cancer Centre, University of Texas, in 1972 having chromosomes like males.

Analysis of their genetics showed that these females did not have chromosomes specific to females, though they had all female characteristics, he said.

While females have two "X" chromosomes, males have one "X" and one"Y" chromosome, these females had one "X" and one "Y" chromosome, Mukherjee said, adding they were not able to reach menstruation.

The male chromosomes, in these females, are believed to have failed to express due to pollutants, which resulted in development of female characteristics, he said.

 
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