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Gastroenterologist shares subtle first signs of 7 chronic illnesses that may not be obvious

Dr Sethi highlights everyday states that may signal health conditions like thyroid dysfunction, diabetes, B12 deficiency, and many more.

Updated on: Dec 11, 2025 07:29 pm IST
By Debapriya Bhattacharya
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While chronic illnesses are becoming common among people at an alarming rate, we are far from experts at recognising the earliest signs of trouble.

Chronic health issues may creep up with early symptoms remaining unrecognised, warns Dr Sethi.(Unsplash)

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Oftentimes, we wait for the most obvious symptoms before seeking professional help for diagnosis.

Taking to Instagram on December 11, Dr Saurabh Sethi, California-based gastroenterologist trained in AIIMS, Harvard, and Stanford, shared the first signs of seven chronic illnesses to spread awareness about the probable danger lurking below the surface.

Thyroid dysfunction

“The first sign of autoimmune issues isn't joint pain. It's morning stiffness and feeling inflamed without a clear cause,” stated Dr Sethi. “Inflammation builds quietly before damage occurs.”

B12 deficiency

Commonly associated with neurological issues, Vitamin B12 deficiency does not initially show up as neuropathy, but rather rising irritability within an individual and progressive brain fog. It is the nerves that provide the first signals, explained the doctor.

Chronic dehydration

Since the brain is the first organ to sense dehydration, the first symptom of the chronic situation is not thirst, but rather “headaches and poor focus.” Such a situation persists in affected individuals even when they are well-rested.

High cortisol

Cortisol disrupts metabolism and leads to fat tissue lining the belly. However, Dr Sethi shared that cortisol levels affect the mood first, and people with high cortisol levels wake up anxious even before the day begins.

“Your gut health is the foundation of all health,” noted Dr Sethi. Keeping an eye out for energy, mood, immunity, cravings and inflammation can help detect many other health issues early and seek the necessary help.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

 

Debapriya Bhattacharya is a Content Producer at Hindustan Times. He started his career in 2022, working in newsrooms in beats like education, US news, trending stories, and entertainment. In his new role in the lifestyle desk, he seeks to deliver a balanced blend of research-driven reporting and creative storytelling from health and recipes to art and culture. Science, philosophy, food and pop culture are what pump his veins and help bring heart to his stories. Debapriya tries to see out subjects that will allow him and readers to explore new frontiers and improve the quality of life for all. The explorations can be both external and internal, as thoughts seek to be as chaotic as the greater universe. As a citizen of the world, Debapriya has been fascinated by the lives of people across the globe throughout time. His curiosity leads him to explore new linguistic and cultural landscapes to broaden his horizons and deepen his understanding of global narratives. Beyond the newsroom, Debapriya loves to participate in debate and theatre, spaces that he considers to be holy grounds for nuance and self-expression. A graduate from Ashutosh College, University of Calcutta, Debapriya completed his Master's degree from the same university in 2022. An ambiverted bibliophile, he loves his solitude as much as he adores stimulating conversations. And despite his reverence for tech, libraries continue to be his favourite place for research.

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