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New pill for senior dogs? Scientists test daily drug that may extend lifespan
Loyal's new pill aims to extend senior dogs' lifespan and improve quality of life.
A new daily pill being developed by US-based biotech firm Loyal is offering hope to pet owners, with early research suggesting it could extend the lifespan of senior dogs while maintaining their quality of life.
According to a report by Good, the experimental drug, called LOY-002, is designed for dogs aged 10 and older, particularly those weighing over 14 pounds.
What is the new dog longevity pill?
LOY-002 is a beef-flavoured, prescription pill currently undergoing regulatory review. It is part of what researchers describe as one of the largest clinical trials in veterinary history focused on extending canine lifespan.
The drug targets a hormone known as Insulin-Like Growth Factor 1 (IGF-1), which plays a key role in growth and metabolism.
While IGF-1 helps puppies develop into healthy adult dogs, it is also linked to faster aging at the cellular level once dogs mature.
How does it work?
By reducing IGF-1 levels, LOY-002 aims to slow down the biological aging process. Scientists say this could lower the risk of age-related diseases, organ decline, and early death, particularly in larger dog breeds, which tend to have higher IGF-1 levels and shorter lifespans.
The drug does not simply improve how dogs feel but is intended to directly impact the underlying aging process, potentially adding years to a dog’s life.
What experts are saying
“Since founding Loyal six years ago, my goal has always been to get the first drug FDA approved for lifespan extension,” said company founder and CEO Celine Halioua.
“This safety acceptance brings us very close to achieving that vision… We are well on our way to bringing the first dog longevity drugs to market,” she added.
The drug has already cleared two out of three required stages for approval by the US Food and Drug Administration, bringing it closer to commercial availability.
Also Read: Looking forward to adopting an Indian dog breed? Check out 5 best indigenous breeds here
When could it be available?
If it receives final regulatory approval, LOY-002 could be available before the end of 2026, according to the report.
While the drug is still under review, veterinarians recommend focusing on proven methods to improve a senior dog’s health. These include regular checkups, a balanced diet, and consistent exercise suited to the dog’s age.
Experts also advise consulting veterinarians before introducing supplements or making major lifestyle changes, especially for dogs with joint issues or chronic conditions.
